| Name | Class year | Notability | Reference(s) |
|---|
| Alfonso Aguilar | 1991 | Chief of the Office of Citizenship in the United States Citizenship and Immigration Services | [194] |
| Richard V. Allen | 1957
MA 1958 | Former United States National Security Advisor | [195] |
| James L. Applegate | 1953 | Democratic member of the Wyoming House of Representatives | [196] |
| James A. Baker | Staff attorney in the United States Department of Justice | [197] |
| Amy Coney Barrett | 1997
JD | Associate Justice of the Supreme Court of the United States | [198] |
| B. Patrick Bauer | 1966 | State Representative (1970–2020), former Speaker | [199] |
| Taylor Benson | 1955 | Wisconsin state senator | [200] |
| Brendan F. Boyle | 1999 | State Representative, Pennsylvania (2009–2015) | [146] |
| Jerry Brady | 1958 | Former Democratic candidate for governor of Idaho and newspaper owner | [201] |
| Joseph Cari Jr. | 1974
JD 1978 | Lawyer, businessman, and public policy expert | [202] |
| John R. Cencich | 2004
J.S.D. 2008 | Former senior international war crimes investigator with the United Nations at the Hague, Netherlands | [203] |
| Jeffrey S. Chiesa | 1987
BA 1987 | New Jersey Attorney General (2012–2013) | [204] |
| Quin Denvir | 1962 | Public defense attorney best known for representing Theodore Kaczynski, as well as Reza Eslaminia of the Billionaire Boys Club | [205] |
| Jenny Durkan | 1980 | United States Attorney for the Western District of Washington (2009–2014) | [206] |
| Ryan Dvorak | 1996 | Indiana State Representative (2002–present) | [207] |
| Charles H. Fahy | 1911 | Former Solicitor General of the United States | [208] |
| Sean Faircloth | 1982 | Maine State Representative (1992–1994; 2002–2008), Maine State Senator (1994–1996), Executive Director Secular Coalition for America | [209] |
| Peter F. Flaherty | 1951
JD | Former mayor of Pittsburgh and deputy United States Attorney General | [210] |
| Emilio M. Garza | 1969
MA 1970 | Judge on the United States Court of Appeals for the Fifth Circuit | [6] |
| Douglas Gonzales | 1959 (Bachelor of Arts) | U.S. attorney and judge of the Louisiana district and circuit courts in Baton Rouge | [211] |
| Camille Gravel | Louisiana defense attorney and gubernatorial advisor | [212] |
| Leo Richard Hamilton | 1949 | Wisconsin State Assemblyman (1987–1993) |
| Thomas Hardiman | BA 1987 | Judge of the United States Court of Appeals for the Third Circuit (2007–present) | [213] |
| Kevin Hasson | MA
JD 1985 | Lawyer and founder of religious law firm | [214] |
| William J. Hochul, Jr. | 1981 | United States Attorney for the Western District of New York (2010–2016) |
| William Tell Johnson | Lawyer, judge and politician | [215] |
| Walter J. Kavanaugh | 1955 | Former New Jersey state Senator (1997–2007), New Jersey state Representative (1976–1997) | [216] |
| Matthew F. Kennelly | 1978
Bachelor of Arts | District Judge, United States District Court for the Northern District of Illinois (1999–present) | [217] |
| John Kilkenny | 1925
LL.B. | Federal Judge: 9th Cir. (1969–1971); D. Or. (1959–1969) | [218] |
| Stanley Kusper | Cook County clerk | [219] |
| Frank LaGrotta | 1980
MA 1981 | Pennsylvania state representative (1987–2006) | [220] |
| Edward Leavy | 1953
LL.B. | Federal Judge: 9th Cir. (1987–1997); D. Or. (1984–1987) | [221] |
| Robert E. Lynch | Wisconsin State Assemblyman (1933–1936; 1943–1958) | [222] |
| Michael Madigan | Illinois State Representative (1971–present), Speaker of the Illinois House of Representatives (1983–1995; 1997–present) and chairman of the Democratic Party of Illinois | [223] |
| Mbuyiseli Madlanga | 1990
LL.B. | Judge of the Constitutional Court of South Africa; appointed on August 1, 2013 | [224] |
| Eduardo Malapit | 1962
JD | Former Mayor of Kauai, Hawaii, first Filipino American mayor in the United States | [225] |
| Jennifer Mason McAward | 1994
BA | Former clerk to Associate Justice Sandra Day O'Connor and current Associate Professor of Law at Notre Dame Law School | [226] |
| Ralph McGehee | 1949 | Former officer for the Central Intelligence Agency who went on to be an outspoken critic of the Agency as the author of Deadly Deceits: My 25 Years in the CIA | [227] |
| William McGurn | 1980 | President George W. Bush's chief speechwriter and chief editorial writer and member of The Wall Street Journal's editorial board | [228] |
| C. E. McIntosh | Wisconsin State Assemblyman (1869–1871) | [229] |
| Jerry Meek | Lawyer and chairman of the North Carolina Democratic Party | [230] |
| Joan Orie Melvin | 1978 | Former Pennsylvania Supreme Court justice, felon | [citation needed] |
| Robert Meza | 1986 | Arizona State Senator (2011–present), Arizona State Representative (2003–2011) | [231] |
| Federico A. Moreno | 1974 | Chief Federal Judge of the Southern District of Florida | [232] |
| Michael Murphy | 1979 | Indiana state representative (1994–2010) | [233] |
| Ralph Neas | 1968 | Politician and former president of the People For the American Way | [234] |
| Paul V. Niemeyer | 1966
JD | Federal Judge: 4th Cir. (1990–present), D. Md. (1988–1990) | [235] |
| Kevin J. O'Connor | 1989 | United States Attorney from Connecticut | [236] |
| Alan Page | 1967 | Associate Justice of the Minnesota Supreme Court; member of the Pro Football Hall of Fame | [237] |
| Louis P. Peck | 1950 (BA)
1951 (JD) | Associate Justice of the Vermont Supreme Court | [238] |
| Condoleezza Rice | 1975
MA | United States Secretary of State and former National Security Advisor | [239] |
| Al Salvi | 1982 | Former member of the Illinois House of Representatives, US Senate Republican nominee and Illinois Secretary of State Republican nominee; managing partner of Salvi & Maher, LLC | [240] |
| John Sears | 1960 | Campaign manager for Ronald Reagan | [241] |
| Matthew J. Slaughter | 1990 | Economist and former member of the Council of Economic Advisers |